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Open access Nov 2026

Subjective cognitive decline as an early marker of cognitive impairment in Parkinson’s disease

Cognitive impairment is one of the non-motor symptoms with the greatest impact on patients and caregiver quality of life. Given its onset and significant relevance during the prodromal phase of Parkinson’s disease (PD), and its potential role as an at-risk state for cognitive impairment, this study investigated the rol...

Gabriel Martinez Tirado, Patricia Martins Conde, S. Sapienza et al. · 0 citations
Open access Nov 2026

Understanding the Pattern of Cognitive Decline in GBA1-Related Parkinson's Disease: An Exploratory Longitudinal Multi-Cohort Study.

OBJECTIVE People with Parkinson's disease (PD) who carry a pathogenic GBA1 variant (PDGBA1) are at higher risk of cognitive impairment than those without the variant (PDGBA1_wildtype). To date, little is known about the pattern and evolution of cognitive decline in PDGBA1. This multicenter study characterized the cogni...

Merle Bode, C. Pauly, S. Jónsdóttir et al. · 0 citations

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