Author

C. Morales

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Open access Jul 2026

Computationally engineered cyclic peptides reduce prion levels in vitro

These results establish a mechanistic link between peptide-induced stabilization of PrPc and inhibition of prion propagation and provide a generalizable framework for designing conformational stabilizers of aggregation-prone proteins.

Elpiniki Paspali, C. Morales, Daria De Raffele et al. · bioRxiv · 0 citations