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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

Author

C. Miano

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Open access Sep 2026

Hierarchical and context-dependent GR-MR signalling governs endogenous corticosteroid decoding in the heart

Endogenous corticosteroids bind both the glucocorticoid receptor (GR) and mineralocorticoid receptor (MR), yet how this shared ligand input is decoded in the heart remains unclear. Previous work established that corticosterone suppresses postnatal cardiomyocyte proliferation through GR. Here we show that corticosteroid...

F. Sacchi, S. Boriati, R. Caliandro et al. · 0 citations

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