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C. McDowell

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Open access Oct 2026

A-88: DOPA Decarboxylase Relates to Hippocampal Atrophy and Amplifies Tau-Associated Memory Dysfunction in Older Women at Risk for Alzheimer’s Disease

Objective: Cerebrospinal fluid (CSF)-derived DOPA decarboxylase (DDC) is a promising biomarker of synucleinopathy; however, its relevance in Alzheimer’s disease (AD)-risk cohorts remains unclear. Research suggests that DDC may index co-pathology contributing to neurodegeneration and memory dysfunction beyond AD patho...

Jordan Stiver, C. McDowell, Xin Wang et al. · 0 citations

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