Review
Open access
Oct 2026
Glucocorticoid receptor modulation as a host-directed strategy for inflammatory priming across chronic disease states
Chronic inflammation is increasingly recognized as a shared feature across neuropsychiatric, neurodegenerative, metabolic, oncologic, and post-infectious disorders, yet treatments mainly target downstream effects. Evidence suggests dysregulated glucocorticoid receptor (GR; encoded by NR3C1 ) signaling may regulate...
R. Slayden, R. Tjalkens, Neil D. Theise et al.
· Frontiers in Pharmacology · 0 citations