Aberrant epigenetic regulation is a central driver of tumorigenesis, and the reversibility of epigenetic modifications underscores their potential as therapeutic targets. Epigenetic factors often function in a highly context-dependent manner, necessitating rigorous study of their dynamic and complex roles. Here, we unc...
Laura Leonhardt, Jia-Zhuan Mei, Audrey M. Hendley et al.· Cancer Research· 0 citations
About 10% of neuroendocrine tumors (NETs) can occur in the context of several different hereditary tumor syndromes, and, in a not negligible number of cases, their diagnosis precedes the clinical identification of the hereditary syndrome. In this context, the role of a pathologist can be crucial in identifying these se...
S. Uccella, C. Luchini, A. Kasajima et al.· Advances in Anatomic Patholo...· 0 citations
A transcriptomic framework is suggested in which PM can be characterized as a distinct niche-conditioned biological entity and support microenvironment-informed diagnostic and therapeutic strategies.
M. Bencivenga, M. Simbolo, Stefano Gobbo et al.· Annals of Surgery· 0 citations
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