Development of resistance to taxane-based chemotherapy, specifically docetaxel (DTX), in advanced prostate cancer is frequent. Natural compounds, such as narciclasine, an alkaloid derived from plants, offer a potentially advantageous approach. Docetaxel-resistant prostate cancer cell lines (DU145RST and PC3RST) were es...
Ranyelison Silva Machado, Kaio S. Gomes, Augusto B. Farias et al.· ACS Omega· 0 citations
The development, differentiation, and homeostasis of adherent cells are regulated by interactions among cells, the extracellular matrix (ECM), and soluble factors. Loss of these contacts induces anoikis, a specific form of apoptosis. Tumor cells acquire resistance to anoikis, enabling them to survive without anchorage,...
Diego Mauro Carneiro Pereira, Ana Paula de Sousa Mesquita, Amanda da Silva Cruz et al.· Molecular Biology Reports· 0 citations
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