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C. Lee

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#protein folding Open access Sep 2026

From stability to specificity: mechanistic insights into the functions of two acyl carrier proteins, ApeE and ApeF, in aryl polyene biosynthesis in A. baumannii

Comparative analysis reveals that ApeE exhibits greater conformational plasticity, enabling it to accommodate bulky APE intermediates, reflecting its role in flexible substrate handling, while ApeE’s flexibility facilitates substrate switching necessary for APE biosynthesis.

Hyun-Wook Cho, C. Lee, Yangmee Kim · 0 citations

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