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Sponsored AI Networking Cookbook: Practical recipes for AI-assisted network automation and development AI Networking Cookbook: Practical recipes for AI-assisted network automation and development

Author

C. Lawrence

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Open access Oct 2026

Repurposing the phospholipase A2 inhibitor, darapladib, to combat multidrug-resistant fungal pathogens, including Candida auris

Candida auris is an emerging multidrug-resistant fungal pathogen and a major global health threat, highlighting the urgent need for new therapeutics. We screened ~2,600 FDA-approved drugs and clinical compounds and identified darapladib (DAL), a phospholipase A2 inhibitor, as a potent antifungal agent against multidrug...

Yehia Elgammal, Ehab A. Salama, Nour M. Alkashef et al. · 0 citations
Open access Sep 2026

Structure-Activity Relationship Profiling of Substituted N-Phthalimidopiperidine Analogs as Broad-Spectrum Antifungal Agents.

SSD2032594 showed a survival benefit in the Caenorhabditis elegans nematode model of C. auris infection, resulting in a ∼30% higher survival rate, and is highlighted as a candidate for antifungal drug development, targeting infections caused by different fungal pathogens.

Matthew P. Dupuis, Nour M. Alkashef, Roman A. Matamoros et al. · 0 citations

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