This chapter outlines a comprehensive protocol for joint embedding of chromatin accessibility and transcriptomic data using best practices developed in laboratories, along with detailed parameter tuning at each step to fully leveraging this pipeline.
Avinash M. Veerappa, C. Guda· Methods in molecular biology· 0 citations
A comprehensive RNA-sequencing analysis of postmortem nucleus accumbens tissue from individuals with OUD and matched controls provides an integrated view of candidate genetic and transcriptomic alterations in OUD and identifies lncRNA-centered regulatory networks and candidate variant-bearing genes as hypothesis-genera...
R. Chakraborty, C. Guda, Avinash M. Veerappa· Frontiers in Cellular Neuros...· 0 citations
KU2046-induced migrastasis appears to operate through spatial decoupling rather than structural degradation, providing a correlative framework to inhibit metastatic dissemination independent of direct cytotoxicity.
Weining Chen, Saadyeh Rashidi, H. Law et al.· bioRxiv· 0 citations
It is proposed that the upregulated lncRNA ENSG00000265613 may enhance malignancy by stabilizing the RNA target ENSG00000582008 in luminal A breast cancer, particularly given its established role in oncogenesis.
C. Guda, Sankarasubramanian Jagadesan, Avinash M. Veerappa· Methods in molecular biology· 0 citations
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