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Open access Aug 2026

Involvement of HOXA3 and chaperone-mediated autophagy in DEHP-induced ferroptosis of mouse Leydig cells via regulating GPX4 expression

Impaired Leydig cell function leads to low testosterone levels, which is associated with male reproductive developmental defects and functional disorders. Exposure to di(2-ethylhexyl) phthalate (DEHP), an endocrine-disrupting chemical, can cause damage to Leydig cells, yet the underlying mechanism remains unclear....

Yan-Yan Liu, C. Guan, Lin-Ling Xu et al. · 0 citations

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