Author

C. Griñán-Ferré

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Review Open access Sep 2026

Epigenetic Hierarchies in Autism from Folate–SAM Metabolism to LSD1 and G9a

Autism spectrum disorder (ASD) is a diverse neurodevelopmental condition involving interactions among genetic, environmental, metabolic, immune, synaptic, and epigenetic factors. This review explores whether disruptions in folate-dependent one-carbon metabolism and S-adenosylmethionine (SAM) availability may increase e...

N. Pérez, Aina Bellver, Fahad Hussain et al. · Biomolecules · 0 citations

Sep 2026

Repurposing antifolates as G9a methyltransferase inhibitors for potential Alzheimer's disease therapeutics via 3D QSAR/pharmacophore mapping and experimental validations.

Abhisek Jana, A. Bellver-Sanchis, K. Barman et al. · Medicinal Chemistry Research · 0 citations

Review Open access Sep 2026

Caenorhabditis elegans as a Model for Studying Nrf2/SKN-1 Activation in Alzheimer’s Disease: Plant Bioactive Compounds and Therapeutic Translation

This review attempts to provide comprehensive understanding of the molecular characteristics and pathological basis of AD, including the altered Nrf2-ARE signaling in AD and the molecular architecture and regulation of the Nrf2-SKN-1 pathway in C. elegans.

A. Bellver-Sanchis, N. Ralchev, Patrizia R. Romanska et al. · International Journal of Mol... · 1 citation