Open access
Oct 2026
Baseline microbial ecology encodes probiotic responsiveness through distinct metabolic and network configurations.
Probiotic efficacy in inflammatory bowel disease varies widely between individuals, and the sources of that variability remain poorly understood. D-lactate is a microbiota-derived metabolite that accumulates during intestinal inflammation and is associated with epithelial barrier dysfunction, which motivated our use of...
Jia-Qi Li, Ahmet Göktuğ Özkurt, Isabel Baertschi et al.
· Cell Reports · 0 citations