Open access
Oct 2026
Pd-Catalyzed Reductive Cyclization Using CO Surrogates: Selective N-N Bond Formation and Access to Indazolo[3,2-a]isoquinolines.
A Pd-catalyzed reductive cyclization of nitroaryl isoquinolines using phenyl formate as a carbon monoxide (CO) surrogate is reported. The method provides selective access to 5,6-dihydroindazolo[3,2-a]isoquinolines, indazolo[3,2-a]isoquinolines, and 8,13-dihydro-7H-indolo[2',3':3,4]pyrido[1,2-b]indazoles from precursors...
S. Di Ciolo, Simone Galiè, A. Silvani et al.
· Journal of Organic Chemistry · 0 citations