Author

C. Finney

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Open access Aug 2026

Cross‐tissue immune profiling of APOE ε4 reveals early dysregulation in Alzheimer's disease

Apolipoprotein E (APOE) ε4 is the strongest genetic risk factor for late‐onset Alzheimer's disease (AD), but its contribution to disease pathogenesis remains incompletely understood.

A. Shvetcov, Shannon Thomson, Mark E. Graham et al. · Alzheimer's & Dementia · 0 citations

Open access Jul 2026

An integrated atlas of RNA to protein concordance across human tissues and cell types

Differential expression studies, single-cell atlases, and target discovery pipelines measure RNA as a proxy for protein. Across human tissues, RNA explains only 40 to 60% of the variance in protein, and no framework resolves which genes reliably translate RNA into protein. We present an integrated atlas that matches si...

C. Finney, A. Shvetcov · bioRxiv · 0 citations