Open access
Sep 2026
CD98hc marks a precursor of human stem cell-derived alpha cells primed for functional maturation
Introduction Pluripotent stem cell-derived alpha cells (SC-α cells) represent a promising component of next-generation cell therapies designed to more fully recapitulate human islet function; however, heterogeneity and the presence of undesired side populations limit their functional maturity and therapeutic potential....
Sean Lewis-Brinkman, Tiana Salomon, Kyle R. Knofczynski et al.
· Frontiers in Endocrinology · 0 citations