Nickel/Photoredox-Catalyzed Dicarbofunctionalization of Alkenes via Ketone C─C Bond Cleavage: Access to an Enantioselective Variant.
In this study, we disclose a general protocol for the three-component difunctionalization of alkenes using nickel catalysis and aliphatic carbonyl precursors that are activated by sp3 C─C bond cleavage. Under visible-light irradiation, this transformation provides an efficient strategy to install two vicinal carbon─car...