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Author

C. Chen

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Open access Oct 2026

Prostaglandin E2-EP2 signalling drives vascular aging by inducing mitochondrial dysfunction and pro-inflammatory phenotypic switching via QSOX1 up-regulation

Vascular aging is a fundamental driver of age-related chronic diseases, in which the phenotypic switching of vascular smooth muscle cells (VSMCs) from a contractile to a pro-inflammatory state plays a critical role. While vascular aging involves multiple pathological processes including endothelial dysfunction, t...

J. Wang, Y. Chen, C. Chen et al. · 0 citations

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