Author

C. C. Filgueiras

3 papers indexed here

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Sep 2026

Caffeine mitigates neuroinflammation and behavioral deficits induced by brain irradiation in mice.

PURPOSE Radiotherapy, a standard treatment for brain tumors, may induce cognitive deficits and neuroinflammatory responses, including increased pro-inflammatory cytokines, microglial and astrocytic reactivity, and alterations in neuronal markers. Caffeine, a widely consumed psychostimulant with reported anti-inflammato...

Mauricio M. S. Borges, G. Oliveira, Heitor G. S. Saraiva et al. · International Journal of Rad... · 0 citations

Open access Oct 2026

Beyond Classical Reward Circuits: Dorsal Striatum Proteomic Alterations in an Adolescent Phencyclidine-Induced Mouse Model of Schizophrenia and Nicotine Use

Schizophrenia and nicotine misuse comorbidity frequently emerges during adolescence. Although the dorsal striatum has received less attention than mesolimbic regions in this context, growing evidence supports its involvement in both schizophrenia-related dysfunction and the transition to compulsive drug-seeking. Here,...

T. P. Souza, Andrés Rodríguez-Vega, A. C. Dutra-Tavares et al. · International Journal of Mol... · 0 citations

Open access Sep 2026

Adolescent or adult exposure to nicotine in Swiss mice: age-dependent and -independent effects on open field and elevated plus maze behaviors and on hormonal parameters associated with anxiety.

Adolescence is a critical period of vulnerability to smoking initiation. However, the neurobiological basis of this association is not well understood. Hence, here we evaluated behavioral parameters, tyrosine hydroxylase content, and catecholamine and corticosterone levels of Swiss mice exposed to nicotine (NIC; 50 μg/...

Bruna Lotufo Denucci, Jemima Isnardo Fernandes, Gabrielly de Oliveira Matos et al. · Physiology and Behavior · 0 citations