Author

C. Blanco-Aparicio

2 papers indexed here

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Open access Aug 2026

A Drug‐Gated, Modular STAb‐T Immunotherapy With External Control

ABSTRACT Living cell therapies lack robust, reversible mechanisms for externally controlling therapeutic activity after administration, limiting their safety and clinical adaptability. Here we engineer a drug‐gated cellular immunotherapy platform in which T cells function as programmable factories that secrete two inac...

S. Luengo-Arias, Carmen Domínguez-Alonso, Ivana Zagorac et al. · Advancement of science · 0 citations

Open access Aug 2026

NGFR-driven suppression of antigen presentation limits CD8+ T cell immunity and response to checkpoint blockade

Immune checkpoint blockade has revolutionized cancer therapy; however, numerous tumors remain resistant by adopting cellular states that impede immune recognition. In this study, we identify the nerve growth factor receptor (NGFR) as a regulator of immune evasion in head and neck squamous cell carcinoma (HNSCC). Geneti...

J. García-Agulló, V. Santos, B. Majem et al. · bioRxiv · 0 citations