Transcriptomic and proteomic Mendelian randomization identifies putative therapeutic targets for thoracic aortic disease
Thoracic aortic aneurysm and dissection (TAA/D) are life-threatening conditions, for which no disease-modifying pharmacological therapies currently exist. Here, we aimed to identify novel molecular targets for TAA/D, through a drug target Mendelian randomization (MR) analysis. Within a Bayesian approach, we integrated...