Author

C. Bayliss

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Open access Sep 2026

Emergence of short-lived meningococci causing focal epidemics can be associated with gene transfer from carriage-associated Neisseria

In March 2026, an unusually large outbreak of invasive meningococcal disease (IMD) in Kent, UK, was linked to attendance at one nightclub over a single weekend. The outbreak organism was a Neisseria meningitidis variant belonging to the longstanding hyperinvasive genotype, cc41/44. Using genome analysis of six isolates...

C. Rodrigues, J. Lucidarme, R. Exley et al. · bioRxiv · 0 citations

Open access Sep 2026

Type I restriction–modification systems regulate gene expression through DNA topology

Abstract This study examines how DNA methylation by both phase-variable and canonical restriction–modification (RM) systems contributes to bacterial gene regulation, using the SpnD39III system of Streptococcus pneumoniae and the prototypical EcoKI system of Escherichia coli. RNA-seq analysis of pneumococcal phase-locke...

Yasmeen Althari, Yong-Kui Chen, A. Menon et al. · Nucleic Acids Research · 0 citations