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Open access Sep 2026

The Next Frontier in Quantitative Co-Clinical Imaging to Advance Functional Precision Oncology

Precision oncology seeks to transform cancer treatment into one tailored for individual patients. Genomic alterations have been the dominant drivers of patient-specific therapeutic strategies. While genomic insights can guide treatment planning, genotype-directed therapies do not guarantee response to therapy. Function...

K. Shoghi, C. Badea, Donna M. Peehl et al. · 0 citations
Open access Aug 2026

Calibration-Aware and Interpretable Graph Learning for Multi-Cohort Diffusion Connectome Brain-Age Modeling

Brain-age models derived from diffusion MRI–based structural connectomes may provide imaging biomarkers of accelerated brain aging, but their biological interpretation and transportability across heterogeneous populations remain uncertain. We developed a calibration-aware and hierarchically interpretable graph-learning...

Alexandra Badea, Ines Poves Acle, Paula Mendez de Inza et al. · 0 citations

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