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C. Audette

1 paper indexed here

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Open access 2016

Tumor Delivery and In Vivo Processing of Disulfide-Linked and Thioether-Linked Antibody−Maytansinoid Conjugates

Antibody−drug conjugates (ADCs) are designed to eradicate cancer cells that express the target antigen on their cell surface. A key component of an ADC is the linker that covalently connects the cytotoxic agent to the antibody. Several antibody−maytansinoid conjugates prepared with disulfide-based linkers such as those...

H. Erickson, W. Widdison, M. Mayo et al. · 0 citations

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