Author

C. Andrade

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Open access Sep 2026

Astrocyte Senescence Disrupts the Extracellular Mitochondrial Compartment and Compromises Bioenergetic Support to Human Neurons

Astrocyte senescence is a recognized feature of brain aging, but its impact on neuronal mitochondrial homeostasis remains poorly defined, particularly in human cells. Here we show that doxorubicin-induced senescence disrupts mitochondrial function in primary human astrocytes and compromises their capacity to sustain ne...

Pedro Amorim, Lívia de Sá Hayashide, Vitor Emanuel Leocadio et al. · Antioxidants · 0 citations

Open access Oct 2026

Capybara Oil‐Based Nanoemulsion Attenuates Obesity‐Induced Renal Injury Through Modulation of Inflammation, Oxidative Stress, and Fibrosis in Mice

ABSTRACT Obesity is a multifactorial disorder associated with systemic metabolic alterations and increased risk of renal injury, largely driven by chronic inflammation and oxidative stress. Bioactive lipids, particularly polyunsaturated fatty acids, have been shown to exert protective effects; however, their instabilit...

P. G. Pereira, L. L. Alves, B. Ciambarella et al. · Cell Biochemistry and Functi... · 0 citations