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Author

Bruce D. Carter

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Open access Oct 2026

Palmitoylation of the p75 neurotrophin receptor is required for retrograde regressive signaling

Target-derived neurotrophins regulate neuronal survival and pruning via retrograde signaling. Unlike Trk receptors, which are transported as transmembrane proteins, the p75 neurotrophin receptor (p75NTR) undergoes regulated intramembrane proteolysis to release a soluble intracellular domain (ICD) that must somehow asso...

Amrita Pathak, Hrishita Das, Pooja Shukla et al. · 0 citations

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