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Briana Santo

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Review Oct 2026

Histone-modifying Enzymes as Therapeutic Targets in Glioma: Biological Rationale and Translational Findings.

Histone-modifying enzymes have emerged as therapeutic targets in glioma, particularly H3K27M-altered diffuse midline glioma. This article reviews the biological rationale for targeting these enzymes and summarizes the current preclinical and clinical evidence for histone deacetylase, methyltransferase, and demethylase...

Briana Santo, A. K. Ahmed, Samuel N. Emerson · 0 citations

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