Exploratory imaging in SWEDD: Insights from dopaminergic PET, synaptic density PET, and volumetric MRI.
OBJECTIVE Scans Without Evidence of Dopaminergic Deficit (SWEDD) refers to individuals with Parkinsonian symptoms but no presynaptic dopaminergic deficit on dopamine transporter (DAT) imaging. Given its likely heterogeneity, we used a multimodal imaging approach to compare SWEDD with Parkinson's disease (PD) and health...