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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

Author

Brian J. Snow

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Open access Sep 2026

Vpu protects HIV-infected cells from antibody-dependent cellular phagocytosis by counteracting tetherin.

It is found that Vpu mutations that impair tetherin antagonism also increase the susceptibility of HIV-infected cells to antibody-dependent cellular phagocytosis (ADCP), and the antiviral activity of tetherin may be amplified in vivo by Fc-mediated antibody effector functions and therefore much greater than initially a...

Brian J. Snow, Nida K. Keles, Ahmed Ali et al. · 0 citations

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