Pegylation modulates ApoE association and hepatic accumulation of DC-Chol-based nanoparticles through steric exclusion.
Findings indicate that PEGylation reduces ApoE association primarily through steric exclusion and highlight PEGylation as a useful strategy for modulating nanoparticle biodistribution.
Mitra Hosseini-Kharat, Anthony D. Wignall, Bradley Chereda et al.
· International journal of pha... · 0 citations