Author

Bowen Zhou

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Open access Jul 2026

CENO: A Genome-Scale World Model for Evolutionary Sequence Interpretation and Programmable Regulatory Design

CENO is introduced, a family of long-context generative genomic world models designed to preserve local DNA grammar while extending usable context to regulatory and chromatin scales and provides a genome-scale sequence world-model framework for sequence interpretation, evolutionary reasoning, gene-scale reconstruction...

Mingqian Ma, Yucheng Wu, Xin Chen et al. · bioRxiv · 0 citations

Preprint Jul 2026

Accurate, Interdisciplinary and Transparent Structure-property Understanding with Deep Native Structural Reasoning

SciReasoner is introduced, a multimodal scientific foundation model for native structural reasoning across proteins, small molecules and inorganic crystals that connects accurate prediction with interpretable scientific inference.

Chen Tang, Yizhou Wang, Jianyu Wu et al. · 1 citation