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Sponsored AI Networking Cookbook: Practical recipes for AI-assisted network automation and development AI Networking Cookbook: Practical recipes for AI-assisted network automation and development

Author

Borja Ibarra

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2 papers indexed here

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Review Aug 2026

Structural and single-molecule insights into the core human mitochondrial DNA replisome

Abstract Replication of human mitochondrial DNA (mtDNA) is essential for the maintenance of oxidative phosphorylation and cellular energy homeostasis. Impairment of this process leads to mtDNA deletions, depletion, and point mutations that underlie a broad spectrum of mitochondrial diseases, as well as contributing to...

Ismael Plaza-G.A, S. Miguez-Amil, Allison M Hayes et al. · 0 citations
Open access Sep 2026

A dedicated motif in human polymerase gamma enables DNA synthesis through replication roadblocks

Mitochondrial DNA (mtDNA) maintenance is essential for cellular homeostasis, and defects in mtDNA replication are linked to a broad spectrum of mitochondrial diseases. During replication, DNA polymerase γ (Polγ) must traverse duplex junctions and stable secondary structures, yet how the human enzyme overcomes these bar...

S. Miguez-Amil, A. Grande-García, Plaza G. A. Ismael et al. · 0 citations

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