Author

Bo Yu

3 papers indexed here

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Review Oct 2026

Cell-death-driven plaque evolution: macrophage fate and opportunities for targeted therapy.

Atherosclerosis (AS) is a lipid-driven chronic inflammatory disease in which pathological progression is profoundly regulated by macrophage fate determination mechanisms. This review explores how macrophages derived from hemogenic endothelial cells and bone marrow contribute to disease development, functioning either a...

Si-Hang Zhang, Yue-Hong Wang, B. Yi et al. · International Immunopharmaco... · 0 citations

Sep 2026

Geraniin alleviates pathological visceral adipose tissue expansion through modulation of β-adrenergic receptor-associated cAMP-LKB1-AMPK signaling in high-fat diet-fed mice.

ETHNOPHARMACOLOGICAL RELEVANCE Geranium (Geranium wilfordii Maxim.) has traditionally been used as a folk medicine in East Asia and Europe. Geraniin, the major bioactive constituent of geranium, has been reported to ameliorate dyslipidemia and insulin resistance, but its effects against adipose metabolic dysfunction re...

Yi Feng, Xiao-Yu Liu, Xin-Yi Zhang et al. · Journal of Ethnopharmacology · 0 citations

Open access Sep 2026

Extracellular Vesicle Packaged TDP43 Derived From ECs Exacerbates Cigarette Tar‐Related Atherosclerosis Progression via Enhancing Macrophage Extracellular Traps

ABSTRACT Smoking acts as a critical risk factor for atherosclerosis (AS), but the precise molecular mechanisms remain unclear. We performed in vivo experiments with TAR‐injected ApoE−/− mice and in vitro co‐culture of macrophages with extracellular vesicles (EVs) from TAR‐treated endothelial cells (ECs). Single‐cell RN...

Xin-Xin Zhu, Yu-Wu Chen, Wei Meng et al. · Advancement of science · 0 citations