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Sep 2026

Novel Isoxazoline Amide Derivatives with Diaryl Sulfide Fragment as Potential Insecticides

Isoxazoline insecticides exhibit broad-spectrum and highly effective insecticidal activity by acting on insect GABA receptors. Existing insecticides have high toxicity towards non-target organisms, such as bees, limiting their practical use. This study utilized an active group splicing approach to create 41 new isoxa...

Zhong-Lu You, Bo-Yi Sun, Zheng-Wei Wu et al. · 0 citations
Jul 2026

Molecular Concatenation of 3,5-Dichloro-2,6-Difluoropyridin-4-amine with Heterocyclic Carboxylic Acids and Evaluation of their Antifungal Activity.

A1 and A2 are identified as promising, bee-safe leads for next-generation SDHI fungicides based on a 3,5-dichloro-2,6-difluoropyridin-4-amine scaffold and disrupt mycelial morphology and inhibit SDH, supported by molecular docking and enzyme activity assays.

Bo-Yi Sun, Hui Wang, Dan-Dan Wang et al. · 1 citation

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