Author

Bo Yang

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Open access Oct 2026

ATF4 Activation Promotes All-trans-Retinal-Driven Retinopathies in Mice

Impaired clearance of all-trans-retinal (atRAL) during the visual cycle leads to retinal degeneration, which is closely associated with autosomal recessive Stargardt disease (STGD1) and dry age-related macular degeneration (dry AMD). Transient activation of activating transcription factor 4 (ATF4) generally supports ce...

Kun-Han Yang, Chao-Feng Yu, Dan-Xue He et al. · Antioxidants · 0 citations