Preprint
Oct 2026
QProtFuse: Query-Guided Layer Fusion for Retrieval-Augmented Protein Function Prediction
QProtFuse is proposed, which uses queries to adaptively fuse multi-layer protein features and jointly learns protein and annotation retrieval through intra-modal and cross-modal contrastive objectives and demonstrates the value of query-guided fusion and complementary training objectives for exploiting a PLM's internal...
Mian-Zhi Pan, Pei-Shuo Liu, Ya-Wen Ouyang et al.
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