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Open access Oct 2026

Pharmacological targeting of FKBPL with rapamycin sensitizes triple-negative breast cancer to ferroptosis.

Triple-negative breast cancer (TNBC) remains a clinically formidable subtype, while resistant to conventional apoptotic cell death pathways, it exhibits a unique and exploitable vulnerability to ferroptosis. Here, we identify the FK506-binding protein-like (FKBPL) as a novel scaffold that dictates ferroptosis sensitivi...

Rong-Hui Li, Hang Ke, Zi-Han Chen et al. · 0 citations
Review Open access Oct 2026

Central-type primitive neuroectodermal tumor of the uterus: Case report and literature review

Primitive neuroectodermal tumors (PNETs) arising in the uterus, particularly those classified as the central-type (cPNET), are exceedingly rare. To date, approximately 30 cases of uterine cPNET have been reported, and their clinicopathological features remain poorly characterized. These tumors typically present as high...

Yi-Ying Lin, Ming-Yu Xie, Rong-Jun Mao et al. · 0 citations

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