Open access
Oct 2026
CLEC4E-Mediated Macrophage Activation Contributes to Host Defense in Acanthamoeba Keratitis.
Purpose Acanthamoeba keratitis (AK) is a vision-threatening corneal infection characterized by intense inflammation and tissue damage. Although innate immunity is critical for host defense against Acanthamoeba, the pattern recognition receptors (PRRs) involved in pathogen sensing remain incompletely defined. This study...
Qing-Quan Shi, Zhen Cheng, Zhen-Yu Wei et al.
· Investigative Ophthalmology... · 0 citations