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Open access Oct 2026

PLA2G4A-driven arachidonic acid metabolic reprogramming promotes NSCLC progression via the HSF1 signaling axis

Aberrant arachidonic acid (AA) metabolism is a hallmark of cancer, and cytosolic phospholipase A2 (PLA2G4A) is the rate-limiting enzyme that initiates this cascade. However, the cell-intrinsic role of PLA2G4A and its downstream signaling mechanisms in non-small cell lung cancer (NSCLC) remain poorly understood. Her...

Wei-Fang Wang, Ze Wang, Kun-Fang Li et al. · 0 citations
Aug 2026

Assessment of Reproductive Risks of Bisphenol S in male BALB/c mice through functional histological and multi-omics investigations.

Bisphenol S (BPS) has increasingly replaced bisphenol A, yet the molecular mechanisms underlying its low-dose hazards on male fertility remain incompletely characterized. This study systematically investigates BPS-induced reproductive toxicity by exposing male BALB/c mice to environmentally relevant doses (0, 10, 100,...

Xiao-Tan Lin, Huan Liu, Wei Ma et al. · 0 citations

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