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Author

Bluma J. Lesch

2 papers indexed here

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Open access Sep 2026

Paternal regulation of H3K4 methylation supports tumor suppressor networks in mammals intergenerationally

Paternally-inherited epigenetic information can influence phenotype in offspring (1). Here, we identify a critical mechanistic contribution of KDM6A (UTX), an X-linked histone modifier and tumor suppressor, in regulating transmissible epigenetic information in mammalian sperm. Paternal loss of KDM6A increases cancer ri...

B. W. Walters, Rachel A. Heuer, Haoming Yu et al. · 0 citations
Open access Sep 2026

Posttraumatic Stress Disorder Epigenome-Wide Association Studies in the Million Veteran Program

Genomic studies have improved our understanding of posttraumatic stress disorder (PTSD) biology. Epigenetic differences in DNA methylation can reflect environmental influences, which are critical in PTSD etiology, and may additionally differentiate between PTSD cases and controls or distinguish severity of PTSD symptom...

Sarah Beck, D. Levey, M. Galimberti et al. · 0 citations

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