Open access
Oct 2026
Sertoli Cell-Specific Deletion of Hsp90aa1 Does Not Overtly Impair Male Fertility in Mice
The stress-inducible molecular chaperone HSP90α, encoded by Hsp90aa1, plays an essential role in male reproduction. Systemic Hsp90aa1 deficiency causes pachytene arrest, germ cell loss, and azoospermia. However, systemic models cannot distinguish effects originating in germ cells from those mediated by the testicular s...
Sunjiangnan Wu, Ling-Peng Kong, Miao Zhu et al.
· Cells · 0 citations