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Bing-Liang Xie

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Open access Aug 2026

Canonically minimal RNA-guided insertion sequences expand into large elements that disseminate antimicrobial resistance

Using high-throughput junction mapping together with large-scale comparative genomics, this work redefined the in vivo structural boundaries, growth, and mobilization of IS110 elements and uncovered a previously unrecognized size continuum extending to ∼100 kb, driven by progressive additions.

Kuang Hu, Bing-Liang Xie, Heng-Yi Yang et al. · 1 citation

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