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Open access Sep 2026

Imeglimin improves mitochondrial quality and protects against lipopolysaccharide-induced acute lung injury by enhancing TXNIP promoter methylation.

This study explores the protective effects and mechanistic pathways of imeglimin in models of lipopolysaccharide (LPS)-induced acute lung injury (ALI). Imeglimin administration significantly enhanced survival rates, mitigated pulmonary edema, and attenuated histopathological lung damage in murine subjects. Furthermore,...

Dan-Dan Li, Yu-Zhou Xiao, Wei-Long Hong et al. · 0 citations
Open access Aug 2026

Effects of Dexmedetomidine on Respiratory Mechanics in Elderly Patients Undergoing Laparoscopic Colorectal Tumor Resection: A Randomized Double-Blinded Trial

Intraoperative administration of Dex in elderly patients undergoing laparoscopic colorectal surgery results in a reduction of lung compliance, an increase in plateau pressure, and a deterioration of the OI.

Lin Yang, Yongheng Cai, R. Tan et al. · 0 citations

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