Tailoring Crystallization Modulators for the Facile Synthesis of One-Dimensional Covalent Organic Frameworks to Boost Ultrasound-Triggered Pyroptosis and Immunotherapy.
Ultrasound (US)-induced tumor cell pyroptosis holds great potential for cancer immunotherapy; however, its efficacy is often constrained by the inadequate reactive oxygen species (ROS) generation of conventional sonosensitizers. Herein, one-dimensional porphyrin-based covalent organic frameworks (designated as TD-anili...