Circulating immune biomarkers indicate patients' immune imbalance and predict their disease severity and poor prognosis in pulmonary tuberculosis.
BACKGROUND A comprehensive understanding of the host immune response and identifying valuable markers to predict disease severity and patient's prognosis is a crucial issue. METHODS Plasma levels of 12 soluble immune checkpoints (sICPs), 12 cytokines/chemokines and blood immune cell subsets were analyzed through flow...