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Author

Bin Xie

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Review Open access Jul 2026

Reader-dependent functional duality of FTO: a context-switching node at the intersection of immune evasion and therapeutic resistance

This review synthesizes current evidence on FTO’s roles at the intersection of tumor immune contexture, immune checkpoint regulation, metabolic reprogramming, and therapeutic resistance and examines how FTO may contribute to immune exclusion through metabolic competition, exosomal signaling, and stromal reprogramming.

Wenjie Tian, Bin Xie, P. Zhan · 0 citations
Open access Jul 2026

A synthetic virus-like assembly unlocks dual-antigen presentation for broad-spectrum anti-SARS-CoV-2 immunity

This characterized virion-mimetic structural vaccine not only induces the production of high-efficiency antibodies against both the spike and N proteins but also elicits robust S1-specific and N-specific CTL responses in animal models, creating an optimal microenvironment for eliciting potent and broad-spectrum adaptiv...

Jingjing Zhang, Fen Zeng, Yan-Mei Li et al. · 0 citations

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