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Oct 2026

Region-specific engineering of a bifunctional alcohol dehydrogenase enables efficient single-enzyme sequential oxidation.

Efficient biocatalytic oxidation of primary alcohols to carboxylic acids is attractive for sustainable synthesis, but complete alcohol-to-acid conversion usually requires coordinated control of sequential oxidation steps and continuous regeneration of oxidized cofactors. Here, we report a region-specific engineering st...

Kun Cao, Zhao Wu, Xiao Ma et al. · 0 citations
Sep 2026

Dynamic Interfacial Catalysis: Calcium Hydroxide Drives Lignocellulose Depolymerization and Structural Reconfiguration toward High-Efficiency Fermentable Sugar Production

Mild pretreatment conditions and high solids loading are essential for the cost-effective conversion of lignocellulosic biomass into biofuels and bioproducts. However, the mechanisms underlying efficient cell wall deconstruction under such conditions remain poorly understood. Here, we investigated densifying lignocel...

Xiang-Xue Chen, Li Xiang, Ting Wang et al. · 0 citations
Open access Sep 2026

Enhanced thermostability and structural integrity of dextransucrase via oxidized dextran-mediated modification.

Dextransucrase DsrD5 synthesizes low-molecular-weight dextran (~5 kDa) but has limited industrial utility because of poor thermal and pH stability. Here, DsrD5 was modified with oxidized dextran (ODX) to improve enzyme robustness while retaining the principal low-molecular-weight product profile. Ammonium sulfate enric...

Chi Chen, Yi-Nuo Shen, Yin-Zhu Wang et al. · 0 citations

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