Sep 2026
RNA-Binding Protein MBNL2 Drives Cardiac Hypertrophy and Dysfunction by Facilitating TPM3 Splicing.
BACKGROUND Cardiac hypertrophy is a major contributor to heart failure development, making its prevention and treatment critical for reducing heart failure-associated mortality. Although alternative splicing is recognized as a key regulatory mechanism in myocardial hypertrophy, the precise pathways involved remain inco...
Yuan-Qi Shi, Si-Qi Sheng, Bin Wang et al.
· Circulation Research · 0 citations