BDH1 Attenuates Macrophage Foam Cell Formation and Inflammation in Atherosclerosis Via Modulating Histone H3K9 Acylation Balance and Activating PPAR Signaling
ABSTRACT β‐Hydroxybutyrate dehydrogenase 1 (BDH1) has been implicated in metabolic disorders. Nevertheless, its function and underlying mechanisms in atherosclerosis (AS) remain ambiguous. A high‐fat diet‐fed apolipoprotein E‐deficient mouse model and oxidized low‐density lipoprotein (ox‐LDL)‐induced RAW264.7 macrophag...