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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

Author

Bin Sun

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Aug 2026

Metallaphotocatalytic Assembly of Unsymmetrical 1,4-Diketones via Dual Acyl Units: Divergent Initiation of Carboxylic Acids and Aldehydes

1,4-Diketones, classic umpolung motifs, have long posed a grand challenge for their efficient synthesis in organic and pharmaceutical synthesis. Herein, we report a nickel/photoredox dual-catalyzed three-component coupling of carboxylic acids, aldehydes, and alkenes. This strategy enables the discriminative introduct...

Xiaohui Zhuang, Xin-Yao Hu, Jia-Yin Wang et al. · 0 citations

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